Abstract:

Cardiovascular disease is a leading cause of mortality and morbidity in octogenarian patients. The number of such patients and the number of percutaneous coronary interventions are increasing.

Methods: literature report is based on data, searched in PubMed database, Elibrary, electronic catalog of the Russian State Library, published until January 2017.

Results: review showed reasons why this group of patients refers to high-risk patients. Also, we analyzed modern approaches to the treatment of such patients, significance of PCI, intraoperative factors affecting the outcome of treatment of patients with myocardial infarction.

Conclusion: worse results of PCI in elderly patients in comparison with younger group have multifactorial reasons. Different authors point on higher percent of comorbidity, and previous MI, worse cardiac function, higher iatrogenity Based on received data, we showed clinical problems in these patients, the solution of which would improve results of treatment of this group of challenging patients. 

References

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7.     Antonsen L., Jensen L.O., Terkelsen C.J., Tilsted H. H., Junker A., Maeng M., Hansen K.N., Lassen J.F., Thuesen L., Thayssen P Outcomes after primary percutaneous coronary intervention in octogenarians and nonagenarians with STsegment elevation myocardial infarction: from the Western Denmark heart registry. Catheter Cardiovasc Interv. 2013; 81:912-919.

8.     Daniel I. Bromage, Daniel A. Jones, Krishnaraj S. Rathod. Outcome of 1051 Octogenarian Patients With STSegment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention: Observational Cohort From the London Heart Attack Group. Journal of the American Heart Association. 2016;5:e003027.

9.     Caretta G., Passamonti E., Pedroni PN., Fadin B.M., Galeazzi G.L., Pirelli S. Outcomes and predictors of mortality among octogenarians and older with ST-segment elevation myocardial infarction treated with primary coronary angioplasty. Clin Cardiol. 2014; 37:9:523-529.

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13.   Semitko S.P. Metody rentgenjendovaskuljarnoj hirurgii v lechenii ostrogo infarkta miokarda u bol'nyh starshego

Abstract:

Aim: was to review the efficiency of complex methods of bleeding prevention in elderly patients with acute coronary syndrome (ACS) receiving combined anticoagulant and antiplatelet therapy during percutaneous coronary interventions (PCI).

Materials and methods: between January of 2011 to 2015 in «Pokrovskaya City Hospital» of St. Petersburg, 1435 PCI were performed in patients with ACS, the percentage of patients older than 80 years was more than 9%. To reduce bleeding risk we used: transradial access, diminished time of eptifibatide infusion, bivalirudin, intraoperative control of activated clotting time (ACT).

Results: significant decrease of bleeding episodes in patients with high risk of bleeding requiring transfusion at 0, 25% in the early postoperative period was shown.

Conclusions: the reduction of the bleeding risk will increase management efficiency among patients undergoing PCI.  

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